https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Comparison of synthetic computed tomography generation methods, incorporating male and female anatomical differences, for magnetic resonance imaging-only definitive pelvic radiotherapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48543 Tue 21 Mar 2023 15:42:15 AEDT ]]> Validation of an MRI-only planning workflow for definitive pelvic radiotherapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48126  99% for criteria of 3%/2 mm and 2%/2 mm. With dose criteria of 1%/1 mm, the pass rate was higher for the male cohort at 96.3% than the female cohort at 93.4%. MRI to sCT anatomical agreement for bone and body delineated contours was assessed, with a resulting Dice score of 0.91 ± 0.2 (mean ± 1 SD) and 0.97 ± 0.0 for the male cohort respectively; and 0.96 ± 0.0 and 0.98 ± 0.0 for the female cohort respectively. The mean absolute error in Hounsfield units (HUs) within the entire body for the male and female cohorts was 59.1 HU ± 7.2 HU and 53.3 HU ± 8.9 HU respectively. Conclusions: A multi-atlas based method for sCT generation can be applied to a standard T1-weighted MRI sequence for male and female pelvic patients. The implications of this study support MRI only planning being applied more broadly for both male and female pelvic sites.]]> Tue 21 Mar 2023 15:07:30 AEDT ]]>